Q. What types of hormonal changes caused by fibromyalgia? Fibromyalgia affects hormones because I feel pain in my back bone. What types of hormonal changes caused by fibromyalgia? A. Have you ever checked your back pain with a doctor? It may or may not be due to fibromyalgia. Low serotonin levels, low growth hormone levels, and low levels of neuropeptide Y, a component of the feel-good hormone neurotransmitter norepinephrine have been associated with fibromyalgia. Elevated levels of substance P acts as a neurotransmitter and signals the body to experience pain. These pains have also been observed in the spinal cord of fibromyalgia patients.
The current research builds on past studies, some of which were performed in the laboratory of Chawnshang Chang, ., at the University of Rochester, which have shown that completely eliminating male hormone receptors, or androgen receptors, in female mice leads to abnormal ovarian function and reduced fertility. To help determine which reproductive tissues, including the hypothalamus, pituitary, and many cells within the ovary, regulate fertility, authors of the current study removed androgen receptors from only ovarian cells, known as granulosa cells, in female mice. Androgen receptors in all other reproductive tissues, including the hypothalamus, pituitary, and other ovarian cells were left intact.