However, what I hear "on the streets" is that men who are low SHBG or just high converters to estrogen tend to do better with 3X weekly subQ injections . I believe the reason for this is that with smaller doses of testosterone cypionate more often, you get a smoother ride with lower estradiol peaks. The reason this is probably important is that if you are low SHBG, then you are going to be higher free estradiol. And, of course, elevated free estradiol causes many issues for us men.
My brother has been compounding my hormones since 2000. I just saw a doctor who ordered blood tests to check my hormone levels, primarily because my hair won't stop falling out. The doctor's office faxed the results to my brother and she had prescribed testosterone cream on the labia. I didn't like that answer and now the doctor is in Australia until mid January. The way my brother explained it is that the testosterone will increase the libido, it will build up muscle tissue and do several other positive things. It is not dangerous to apply to the labia. I am going to call the office and ask that another physician explain the results to me. Compounding HRT is the way to go. The pharmacist can closely duplicate the hormones naturally produced in your body when menopause causes them to produce less.