Long term testosterone use side effects

Finally, this study clearly shows that different outcomes plateau at different time points. For ex. the significant improvements in blood cholesterol and triglycerides (lipids) reached a plateau after 3-4 years of TRT, while the decrease in HbA1c was progressive and statistically significant up to five years of testosterone treatment. Importantly and interestingly, the reductions in waist circumference and body weight (and percentage change in body weight) were statistically significant at the end of each year compared to the previous year over the first five years, and even at the end of the sixth year compared to fifth year. This is an unusual and remarkable finding, as obesity interventions (both drugs and lifestyle changes) commonly are most effective the first year, and thereafter progressively lose their efficacy. 57-59  As this 6-year long study demonstrates, testosterone treatment excels in this regard. Let’s hope in the near future this information will reach doctors working with patients who are sedentary, obese and suffer from cardio-metabolic complications.

On the days that you’re most tired, you may also find that you’re most forgetful and unfocused. Sleep helps us refine how we store memory, but a lack of sleep can lead to permanent cognitive issues, such as memory loss. According to a University of California, Berkeley,  study in the journal Nature Neuroscience , researchers found memories may be getting stuck in the hippocampus — the part of brain involved in memory forming, organizing, and storing — due to the poor quality of deep “slow wave” sleep, which is then overwritten by new memories. In addition, sleep deprivation can cause brain deterioration, which may help explain memory loss in the elderly.

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2) The Journal of Sexual Medicine, Jul 2006, 3(4):716-722, "Testosterone:Estradiol Ratio Changes Associated with Long-Term Tadalafil Administration: A Pilot Study" 3) Journal of the American College of Cardiology, Dec 1996, 28(7):1652-1660, "Cardiovascular Effects of Exercise: Role of Endothelial Shear Stress"

Long term testosterone use side effects

long term testosterone use side effects

2) The Journal of Sexual Medicine, Jul 2006, 3(4):716-722, "Testosterone:Estradiol Ratio Changes Associated with Long-Term Tadalafil Administration: A Pilot Study" 3) Journal of the American College of Cardiology, Dec 1996, 28(7):1652-1660, "Cardiovascular Effects of Exercise: Role of Endothelial Shear Stress"

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